Byung Ho Lee Selected Research

Oral Administration

9/2020	KR-39038, a Novel GRK5 Inhibitor, Attenuates Cardiac Hypertrophy and Improves Cardiac Function in Heart Failure.
3/2017	A novel urotensin II receptor antagonist, KR-36996, improved cardiac function and attenuated cardiac hypertrophy in experimental heart failure.
11/2016	A urotensin II receptor antagonist, KR36676, decreases vascular remodeling and inflammation in experimental pulmonary hypertension.
3/2009	Melanin-concentrating hormone-1 receptor antagonism and anti-obesity effects of ethanolic extract from Morus alba leaves in diet-induced obese mice.

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Byung Ho Lee Research Topics

Disease

10	Spinal Stenosis (Stenosis, Spinal) 04/2024 - 10/2012
8	Hypertrophy 09/2020 - 07/2006
7	Pain (Aches) 09/2023 - 03/2013
6	Neoplasms (Cancer) 11/2019 - 05/2011
6	Ischemia 01/2009 - 02/2004
5	Inflammation (Inflammations) 09/2018 - 05/2011
5	Myocardial Infarction 03/2017 - 10/2005
4	Hypoxia (Hypoxemia) 08/2021 - 03/2006
4	Heart Failure 09/2020 - 07/2006
4	Infarction (Infarctions) 03/2017 - 10/2005
3	Infections 09/2023 - 10/2020
3	Obesity 03/2022 - 03/2009
3	Cardiotoxicity 03/2022 - 02/2003
3	Cardiomegaly (Heart Hypertrophy) 09/2020 - 11/2016
3	Autoimmune Diseases (Autoimmune Disease) 11/2019 - 04/2009
3	Atherosclerosis 05/2017 - 10/2002
3	Fibrosis (Cirrhosis) 03/2017 - 02/2013
3	Cardiovascular Diseases (Cardiovascular Disease) 03/2017 - 01/2013
3	Reperfusion Injury 04/2009 - 02/2004
3	Coronary Occlusion 01/2009 - 10/2005
2	Hemorrhage 10/2022 - 05/2010
2	Wounds and Injuries (Trauma) 02/2022 - 07/2007
2	Pathologic Constriction (Stenosis) 01/2022 - 10/2002
2	Pulmonary Hypertension 03/2017 - 11/2016
2	Osteoporosis 11/2014 - 03/2013
2	Vascular Diseases (Vascular Disease) 07/2014 - 10/2002
2	Discitis 01/2014 - 09/2012
2	Critical Illness (Critically Ill) 03/2013 - 02/2012
2	Bone Resorption 03/2013 - 05/2012
2	Fever (Fevers) 03/2013 - 02/2012
2	Body Weight (Weight, Body) 03/2009 - 07/2006
2	Acidosis 03/2006 - 03/2005
2	Contracture 03/2005 - 02/2004
1	Spondylolisthesis 11/2023
1	Tibial Fractures (Fracture, Tibial) 09/2023
1	Necrosis 09/2023
1	Infertility (Sterility) 01/2023
1	Congenital Abnormalities (Deformity) 01/2022
1	Kyphosis 01/2022
1	Spinal Cord Diseases 01/2022
1	Mental Disorders (Mental Disorder) 01/2021
1	Lordosis 10/2020
1	Sacroiliitis 02/2020
1	Glaucoma 01/2020

Drug/Important Bio-Agent (IBA)

5	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 06/2007 - 02/2004
3	Biomarkers (Surrogate Marker)IBA 10/2020 - 07/2006
3	urotensin IIIBA 03/2017 - 11/2016
3	Proteins (Proteins, Gene)FDA Link 11/2016 - 04/2009
3	Messenger RNA (mRNA)IBA 08/2016 - 04/2009
3	Vitamin D FDA LinkGeneric 03/2013 - 05/2012
3	Adenosine Triphosphate (ATP)IBA 03/2006 - 02/2004
3	Guanidine (Guanidine Nitrate)FDA Link 03/2006 - 02/2004
2	melanin-concentrating hormone receptorIBA 03/2022 - 03/2009
2	Ether (Diethyl Ether)IBA 03/2022 - 01/2020
2	ElementsIBA 01/2022 - 04/2009
2	Angiotensin IIIBA 09/2020 - 08/2013
2	G-Protein-Coupled Receptor Kinase 5IBA 09/2020 - 11/2016
2	Phosphotransferases (Kinase)IBA 09/2018 - 11/2010
2	KR-36996IBA 05/2017 - 03/2017
2	benzothiopheneIBA 03/2017 - 03/2006
2	Therapeutic UsesIBA 03/2017 - 11/2014
2	CytokinesIBA 10/2014 - 02/2013
2	rho-Associated KinasesIBA 08/2013 - 01/2013
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 05/2013 - 02/2012
2	AntipyreticsIBA 03/2013 - 02/2012
2	Sodium-Hydrogen ExchangersIBA 07/2007 - 10/2005
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 06/2007 - 10/2005
2	Troponin IIBA 06/2007 - 10/2005
2	N- (4- cyano- benzo(b)thiophene- 2- carbonyl)guanidineIBA 06/2007 - 03/2006
2	IsoenzymesIBA 06/2007 - 10/2005
2	BenzopyransIBA 07/2006 - 02/2004
2	Phosphocreatine (Neoton)IBA 03/2006 - 03/2005
2	Protein Isoforms (Isoforms)IBA 03/2006 - 03/2005
2	GlycogenIBA 03/2006 - 03/2005
2	(5- (2- methoxy- 5- chloro- 5- phenyl)furan- 2- ylcarbonyl)guanidineIBA 10/2005 - 03/2005
1	MetalsIBA 09/2023
1	Sex AttractantsIBA 01/2023
1	Tranexamic Acid (AMCA)FDA Link 10/2022
1	Appetite Depressants (Anorectics)IBA 03/2022
1	KR 31831IBA 02/2022
1	Mitogen-Activated Protein KinasesIBA 08/2021
1	Oxygen (Dioxygen)IBA 08/2021
1	Deferoxamine (Desferal)FDA LinkGeneric 08/2021
1	ORALIT (ORS)IBA 01/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2020

Therapy/Procedure

6	Decompression 01/2022 - 07/2014
6	Therapeutics 05/2017 - 05/2010
4	Oral Administration 09/2020 - 03/2009
3	Pedicle Screws 11/2023 - 03/2016
2	Analgesia 05/2016 - 05/2013
2	Curettage 01/2014 - 09/2012
1	Bone Screws 04/2024
1	Operative Surgical Procedures 01/2022
1	Laminoplasty 01/2022
1	Antibiotic Prophylaxis 01/2021
1	Minimally Invasive Surgical Procedures 10/2020
1	Ligation 09/2020
1	Arthrodesis 02/2020
1	Early Ambulation 02/2020
1	Debridement 02/2020